PatentsÂ
Innovative solutions in tissue engineering and advanced biomaterials.
3D printed bioresorbable material patent
2026 | PATENT PENDING
Priviledge information as of August, 2026
augumentation device patent
2026 | PATENT PENDING
Priviledge information as of August, 2026
Patterned hydrogels with tunable properties
2025 | WO2026080889A1
A patented 3D bioprinted perfused intra-lattice scaffold (PILS) platform with dynamically tunable mechanical and biological properties to tailor matrix microenvironments for advanced cell culture and tissue engineering for assessing equilibration time of a compound, and studying metabolic rates.
Human vascularized integrated organ system "Gen4"
2024 | 2017452-0009 (PATENT PENDING)
A 3D-printed Human Vascularized Integrated Organ System (H-VIOS) "Gen 4" platform designed for ease use of Organs-on-a-chip withing a high-throughput system.Â
Human vascularized integrated organ system "NAME?"
2024 | 2017452-0010 (PATENT PENDING)
Spec same as the 3D-printed Human Vascularized Integrated Organ System (H-VIOS) "Gen 4" platform with emphasis on platform (i.e., polymer platform + hydrogel chip + active cells).Â
Awards & Honors
Selected recognitions and distinctions of career achievements in biomaterials and tissue engineering.
CGS/ProQuest Distinguished Dissertation Award      Â
2020 | Michigantech University, MTU
Professional Development Award ($5,000)
2019 | UCF College of Graduate Studies
Brakta Rath Research Award ($2,000)
2019 | VP for Research/ MTU
Dean's Outstanding Scholarship Award
2018 | Biomedical Engineering Department, Graduate School, MTU
PhD Graduate Research Scholarship Award
Kenneth L. Stevenson Biomedical Engineering Fellowship ($5,000)
2018 | Michigantech University, MTU
2014 | Michigantech University, MTU
Press Releases & Media
Selected news and announcements about our company and its technology.
CNN HEALTH, 2026. Biomedical engineer Ameya Narkar holds a breast tissue scaffold shortly after it came off a 3D printer. (GenesisTissue)
GenesisTissue Selected for MedTech Innovator 2026 Accelerator Cohort & MTI Index
Business Wire / MedTech Innovator (MTI) · May 27, 2026
GenesisTissue Inc. was selected as one of 65 medical technology startups—chosen from over 1,800 global applicants (top 4%)—to join the prestigious MedTech Innovator (MTI) 2026 Accelerator Cohort. selected for both the main cohort and the specialized ASPS Plastic Surgery track, GenesisTissue will received corporate mentorship and compete for non-dilutive accelerator funding.
Systemic Bio Wins Prestigious SLAS 2025 Innovation Award for Bioprinted Organ-on-a-Chip Platform
3D Systems & Systemic Bio · GlobeNewswire | February 5, 2025
Systemic Bio was awarded the prestigious SLAS 2025 Innovation Award for its breakthrough h-VIOS™ organ-on-a-chip platform, recognizing top technological advancements in laboratory science and drug discovery.
Relevant Publications
pH Responsive and Oxidation Resistant Wet Adhesive based on Reversible Catechol?Boronate Complexation
Chem. Mater. (2016)
By copolymerizing dopamine methacrylamide and phenylboronic acid, researchers developed a smart mussel-inspired adhesive that achieves reversible wet adhesion by forming dynamic catechol–boronate complexes. This structural design shields catechol from irreversible oxidation, effectively solving a major stability limitation of traditional wet adhesives while enabling pH-triggered bond switching.
Effect of Ionic Functional Groups on the Oxidation State and Interfacial Binding Property of Catechol-Based Adhesive
Biomacromolecules (2018)
By systematically mapping catechol autoxidation across varying microenvironments, this study reveals that anionic side chains buffer local pH to preserve active catechol groups for robust wet-surface adhesion, whereas cationic amine groups accelerate covalent crosslinking to boost internal cohesion. These findings establish clear molecular design principles for tuning the balance between interfacial binding and bulk toughness in next-generation mussel-inspired bio-adhesives and hydrogels.
Catechol-Functionalized Chitosan: Optimized Preparation Method and Its Interaction with Mucin
Langmuir (2019)
By identifying that traditional synthetic protocols trigger premature autoxidation, this study establishes that maintaining strict acidic conditions (pH < 5) during synthesis is essential to preserve unoxidized catechol groups on chitosan backbones. This optimized preparation restores functional catechol integrity, proving that mucoadhesion relies primarily on rapid non-covalent physical interactions rather than immediate oxidative covalent crosslinking.
Smart biomaterial platforms: Controlling and being controlled by cells
Biomaterials (2022)
By developing an instant bioadhesive synthesized from highly branched aminoethyl gelatin end-grafted with abundant catechol, this study demonstrates rapid, robust sealing on wet biological tissues via dual-mode cross-linking within 10 seconds. In vivo evaluations confirm that this tissue-adhesive platform effectively seals arterial anastomoses and stops severe internal organ bleeding while promoting subsequent wound healing through timely biodegradation.
Rapidly responsive smart adhesive-coated micropillars utilizing catechol–boronate complexation chemistry
Soft Matter (2019)
By coating catechol–boronate smart adhesive hydrogels onto microfabricated PDMS pillars, researchers dramatically increased the material's surface-area-to-volume ratio. This microstructural integration accelerated ion diffusion, allowing the system to rapidly switch between strong wet adhesion at pH 3 and deactivation at pH 9 within just one minute.